About heart disease and God protect us and you

Cause heart disease when they gather lumps of fat on the walls of blood vessels from the inside, which leads to a narrow stream of blood. This consists of the blocks when the interaction of fatty amino acid called homocysteine ​​with cholesterol, which is deposited on the arteries that feed the heart. The increase in the amount of homocysteine ​​may cause material damage to the material that envelop the vessel walls, which will accelerate in the composition of the fat and with whom research has shown that increasing the amount of substance homocysteine ​​in women than doubled the incidence of heart disease.
Defines stroke as a blockage fully artery caused by blood clotting, or blood clot, preventing access of oxygen to the member who fueled this artery, indicating that in most cases get a blood clot in the artery injured calcification or stiffness resulting from the concentration of cholesterol in the inside and its interaction with Platelet

Reasons that lead to heart disease:
There are many factors that interfere with each other and cause heart disease and the incidence of stroke is the most important of these factors:
Age, heredity, high blood pressure, diabetes, high cholesterol and triglycerides, obesity, lack of sport and activity, and increase the level of homocysteine ​​in the blood, smoking, drinking alcohol, unhealthy food.
When the overlap of genetic factors with other factors increase the likelihood of heart disease
Among the most important genes and related to the occurrence of heart disease and stroke are:

Factor V Leiden, prothrombin, methylenetetrahydrofolate (MTHFR)


And prothrombin mutation in the gene produces an abnormal prothrombin because it affects a series of blood clots because the prothrombin one important factor in the series.
The mutation in the gene for Factor V Leiden FVL affect the worker, who becomes resistant to activated protein C (a type of protein helps in the process of balance between blood clotting and its liquidity and working to stop the clotting process at a certain point).
The genetic defect in the (MTHFR) is performed to increase the proportion of Alhmusstin in the blood, which reacts with the cholesterol is deposited on the wall of blood vessels.

In a study conducted on 198 patients from DVT blood clot disease found that 90 (45.5%) patients of them had mutations in one of these three genes. It has been observed that the mutation in the gene for Factor V Leiden and prothrombin gene more impact on the patients heart of Jane (MTHFR).

Diagnosis of genetic factors:
In addition to clinical examinations and laboratory tests conducted by a doctor for heart patients or from patients suffered from a stroke, it is necessary to examine the genetic factors and the need to keep the patient under the boom continued treatment.
The diagnosis is made by examining the genetic material (DNA). And disclosure of the boom using the technique all the PCR and by which the doubling of genetic material and separated electrically after the addition of the dye color's (DNA). Which show the presence of mutation or non-existence through the vision of the genetic material using a UV radiation.